Susan Muller-Weeks, Ph.D.
E-mail: muller@umdnj.edu
Phone: 856 566-6097
Fax: 856 566-6291
Office: Science Center 130
Address:
Department of Molecular Biology
UMDNJ-SOM
2 Medical Center Drive
Stratford, NJ 08084

Major Research Interests:

Cell cycle control mechanisms and DNA Repair; gene regulation

Recent Publications:

Caradonna, S. and Muller-Weeks, S. (2001) The nature of enzymes involved in uracil-DNA repair: Isoform characteristics of proteins responsible for nuclear and mitochondrial genomic integrity. Current Protein and Peptide Science 2,335-347

Boesze-Battaglia, K. and Muller-Weeks, S. (2001) Peripherin/rds. Encyclopedia of Molecular Medicine.

Muller-Weeks, S., Boesze-Battaglia, K., and Fitzgerald, C., (2002) Deletional analysis of the rod photoreceptor cell peripherin/rds carboxy terminal region. Exp. Eye Res. 75:143-154

Elateri, I., Tinkelenberg, B., Hansbury, M., Caradonna, S., Muller-Weeks, S. and Ladner, R. (2003) hSMUG1 can functionally compensate for Ung1 in the yeast Saccharomyces cerevisciae. DNA Repair 1,315-323.

Mandola, M.V., Stoehlmacher, J., Muller-Weeks, S., Cesarone, G., Yu, M.C., Lenz, H-J. and Ladner, R.D. (2003) A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activation. Cancer Res. 63,2898-2904.

Elateri, I., Muller-Weeks, S., and Caradonna, S. (2003) The transcription factor, NF1/CTF plays a positive regulatory role in expression of the hSMUG1 gene. DNA Repair (in press)

Muller-Weeks, S. , Mastran, B., and Caradonna, S. The Nuclear Isoform of the Highly Conserved Human Uracil-DNA Glycosylase Is an Mr 36,000 Phosphoprotein. Journal of Biological Chemistry, Vol. 273, No. 34, pp. 21909-21917, 1998.

Caradonna, S., Ladner, R., Hansbury, M., Kosciuk, M., Lynch, F., and Muller, S. Affinity purification and comparative analysis of two distinct human uracil-DNA glycosylases. Experimental Cell Research, (1996) 222:345-359.

Muller-Weeks, S.J. and Caradonna, S. Specific Association of Cyclin-like Uracil-DNA Glycosylase with the Proliferating Cell Nuclear Antigen. Experimental Cell Research 226, 346-355 (1996)

Muller, S.J. and Caradonna, S. (1993). Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycoslyase. Journal of Biological Chemistry 268, 130-139.

Muller, S.J. and Caradonna, S. (1991). Characterization of a Human cDNA Encoding Uracil-DNA Glysocylase. Biochemicia Biophysica Acta 1088, 197-207.